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To evaluate the effects of chondrocyte specific RUNX2 overexpression on skeletal development, we generated Col2a1 CreERT2 embryos 34 with one or two copies of the R26 Runx2 allele 33 Col2a1 CreERT2; R26 Runx2 and Col2a1 CreERT2; R26 Runx2 Runx2, respectively tamoxifen price 2003 Jul; 9 7 1618 20

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