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Cancer stem cells CSCs, with strong self renewal capability, have been demonstrated to contribute to tumorigenesis, therapy resistance, and also metastasis, which could result in RT failure what happens if a woman takes a mans viagra Show More Northern Centre for Cancer Care, Newcastle upon Tyne, United Kingdom; Department of Medical Oncology, VU University Medical Center, Amsterdam, Netherlands; UMC Utrecht Cancer Center, Utrecht, Netherlands; Universitair Ziekenhuizen Leuven, Leuven, Belgium; The Royal Marsden and Institute of Cancer Research, Sutton, United Kingdom; Phase I Early Clinical Trials Unit, Antwerp University Hospital, Edegem, Belgium; The Experimental Cancer Therapy Unit, Herlev Hospital, Herlev, Denmark; Universitair Ziekenhuis, Brussels, Belgium; Ghent University Hospital, Heymans Institute of Pharmacology, Ghent, Belgium; CHU Sart Tilman Liege and Liege University, Liege, Belgium; Institut BergoniГ©, Department of Medical Oncology, Bordeaux, France; King s College London at Guy s Hospital, London, United Kingdom; GZA Ziekenhuizen campus Sint Augustinus, Antwerp, Belgium; AstraZeneca, Gaithersburg, MD; AstraZeneca, Macclesfield, United Kingdom; AstraZeneca, Cambridge, United Kingdom; University of Manchester, The Christie Hospital NHS Foundation Trust, Manchester, United Kingdom